Ohio State/NINDS Neuroscience Core Grant - P30-NS045758

There are 28 research projects on the Ohio State University campus that are funded by the National Institute of Neurological Diseases and Stroke. This group of investigators brings together not only a common need for animal and transgenic models to study brain development, function, disease, and injury, but also a diverse spectrum of synergistic expertise. A broad base of additional core facility users with funding from other NIH institutes and/or NSF, with research interests of immediate relevance to neuroscience, has also been identified. The primary purpose of the core facility is to enhance investigator access to a variety of animal model systems currently available for neuroscience research at Ohio State.

Neuroscience Core Facility aims:

• to support current NINDS-funded research projects
• to facilitate interactive projects amongst these investigators
• to provide support for other users around the Ohio State campus
• to facilitate interactions amongst basic and translational researchers throughout the University

A Genetics Core, as well as supporting Rodent Behavior, Electrophysiology, and Confocal Microscopy & Imaging Cores, have been constructed.

Current projects being supported by the Core Facility include:

• spinal cord injury and regeneration
• experimental stroke outcome and recovery
• the genetics of Spinal Muscular Atrophy
• genetics of Autism
• mechanisms of Huntington’s Disease excitotoxicity
• basic research projects in sensorimotor processing, growth cone guidance, axonal and dendritic movements of macromolecules, and many more