Associate Professor

Department of Molecular Genetics and
Center for Molecular Neurobiology

Ph.D.: Indiana University
Post-doctoral Training: University of California, Berkeley

Center for Molecular Neurobiology
The Ohio State University
125A Rightmire Hall
1060 Carmack Road
Columbus, OH 43210

Phone: 614-292-5106
Fax: 614-292-5379
E-mail: Seeger.9@osu.edu

Link to NLM & NIH PubMed publications list for Mark A. Seeger (last 10 years)

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Research Area:

• Molecular mechanisms of axon guidance

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Research Description:

The goal of our research is to understand how complex nervous systems are assembled during development. More specifically, we want to understand the molecular mechanisms that direct proper wiring of the nervous system, the processes of axon guidance and synaptic target recognition. To address these questions we utilize Drosophila as our model system where we can take full advantage of a powerful array of genetic, molecular, and cellular approaches. We are also investigating how our favorite families of axon guidance cues and their receptors evolve. By examining these genes and their spatial patterns of expression in other flies, mosquitoes, and beetles, we hope to fain insights into the evolution of axon guidance pathways and developmental mechanisms in general.

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Techniques and Models:

• Genetic, molecular and cellular approaches using Drosophila