Publications supported by the Core Grant (Current as of March 2008)

Ankeny, D.P. and Popovich, P.G. (2007) CNS and non-CNS antigen vaccines exacerbate neuropathology caused by nerve injury, European J. Neuroscience, 25(7):2053-64.

Basso D.M, Fisher L.F, Anderson A.J, Jakeman L.B, McTigue DM, Popovich P.G (2006)  Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J Neurotrauma, 23: 635-659.

Benderlioglu Z, Dow E, Pyter L.M. (2007).  Neonatal exposure to short days and low temperatures blunts stress response and yields low fluctuating asymmetry in Siberian hamsters. Physiology & Behavior, 90:459-465.

Boulant, J.A.  (2006).  Neuronal basis of Hammel's model for set-point thermoregulation. Journal of Applied Physiology.  100: 1347-1354.

Boulant, J.A.  (2006).  Heat-induced membrane depolarization: an unlikely mechanism of central thermosensitivity. Point-Counterpoint article.  American Journal of Physiology  290: R1479-R1484.

Carrel, T. L., McWhorter, M. L., Workman, E. Zhang, H., Wolstencroft, E. C., Lorson, C., Bassell, G., Burghes, A. H. M., and Beattie, C. E. (2006) SMN function in motor axons is independent of functions required for snRNP biogenesis. Journal of Neuroscience 26: 11014-11022. Highlighted in This Week in the Journal.

Cheng, H.Y., Dziema, H., Papp, J., Mathur, D.P., Koletar, M., Ralph, M.R., Penninger, J.M., and Obrietan, K. (2006) The molecular gatekeeper Dexras1 sculpts the photic responsiveness of the mammalian circadian clock. J Neurosci. 26(50):12984-95. See correction: J. Neurosci. April 18, 2007, 27(16).

Choi, Y.S., Lin, S.L., Lee, B., Kurup, P., Cho, H.Y., Naegele, J.R., Lombroso, P.J., and Obrietan, K. (2007) Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase. J. Neurosci. 27, 2999-3009.

Colton, C.K. and Zhu, M.X. (2007) 2-Aminoethoxydiphenyl borate as a common activator of various TRPV channels.  Handb Exp Pharmacol. 179:173-187.

Gliem, M., Weisheit, G., Mertz, K.D., Endl, E., Oberdick, J., and Schilling, K. (2006) Expression of classical cadherins in the cerebellar anlage: Quantitative and functional aspects. Mol. Cell. Neurosci. 33, 447-458.

Hu, H.Z., Xiao R., Wang, C., Gao, N., Colton, C.K., Wood, J.D., and Zhu, M.X. (2006) Potentiation of TRPV3 channel function by unsaturated fatty acids.  J. Cell Physiol. 208, 201-212.

Ignatius, M. S., Moose, H. E., El-Hodiri, H. M. and Henion, P. D. (2008). colgate/hdac1 repression of foxd3 expression is required for mitfa-dependent melanogenesis. Dev. Biol. 313, 568-583.

Jakeman, L.B., Chen, Y., Lucin, K.M., and McTigue, D.M. (2006) Mice lacking L1 cell adhesion molecule have deficits in locomotion and exhibit enhanced corticospinal tract sprouting following mild contusion injury to the spinal cord. Eur. J. Neuroscience: 23, 1997–2011.

Kigerl, K.A., Rivest, S. Hart, R.P., Satoskar, A.R., Popovich, P.G. (2007) Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury, J. Neurochemistry,102, 37-50.

Lee, B., Dziema, H., Lee, K.H., Choi, Y., and Obrietan, K. (2007) CRE-mediated transcription and COX-2 expression in the pilocarpine model of status epilepticus. Neurobiol. Dis. 25, 80-91.

Li, Q.M., Tep, C., Yune, T.Y., Zhou, X.Z., Uchida, T., Lu, K.P., and Yoon, S.O. (2007). Regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. J. Neurosci. 27, 8395-8404.

Longbrake, E.E., Lai, W., Ankeny, D.P., and Popovich, P.G. (2007) Characterization and modeling of monocyte-derived macrophages after spinal cord injury. J. Neurochem. 102, 1083-1094.

Lucas, M. E., Muller, F., Henion, P. D. and Rohrer, H. (2006) The bHLH transcription factor Hand2 is essential for noradrenergic differentiation of sympathetic neurons. Development 133, 4015-4024.

Lucin, K.M., Sanders, V.M., Jones, T.B., Malarkey, W.B., Popovich, P.G. (2007) Impaired antibody synthesis after spinal cord injury is level-dependent and is due to sympathetic nervous system dysregulation, Experimental Neurology., 207, 75-84.

Martin, L.B., Glasper, E.R., Nelson, R.J. and DeVries, A.C. (2006) Prolonged separation delays wound healing in California mice. Physiology & Behavior, 87: 837–841.

McTigue DM, Tripathi R, Wei P (2006) NG2 co-localizes with axons and is expressed by a mixed cell population in spinal cord lesions. J Neuropathol Exp Neurol., 65, 406-420.

McTigue DM, Tripathi R, Wei P, Lash AT.  (2007) PPARgagonist Pioglitazone improves tissue sparing and locomotor recovery after spinal cord injury. Exp Neurol. 205, 396-406.

McWhorter, M. L., Horan, E. S., Burghes, A. H. M., and Beattie, C. E. (2008) The SMN binding protein Gemin2 is not involved in motor axon outgrowth. Dev. Neurobiol. 2008 Feb 1;68(2):182-94.

Nambiar, R. M., Ignatius, M. S., and Henion, P. D. (2007). Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration. Mech. Dev. 124, 682-698.

Pyter, L.M., Reader, B.F., and Nelson, R.J. (2005). Short photoperiods impair spatial learning and alter hippocampal dendritic morphology in adult male white-footed mice (Peromyscus leucopus). Journal of Neuroscience, 25: 4521-4526.

Pyter. L.M & Nelson, R.J.  (2006).  Enduring effects of photoperiod on affective behaviors in Siberian hamsters (Phodopus sungorus).  Behavioral Neuroscience, 120:125-134.

Pyter, L.M., Trainor, B.C., & Nelson, R.J. (2006). Testosterone and photoperiod interact to affect spatial learning and memory in adult male white-footed mice (Peromyscus leucopus). European Journal of Neuroscience, 23:3056-3062.

Pyter, L.M., Adelson, J.D., & Nelson, R.J.  (2007).  Short days increase hypothalamic-pituitary-adrenal axis responsiveness.  Endocrinology 148, 3402-3409.

Serinagaoglu, Y., Zhang, R., Zhang, Y., Zhang, L., Hartt, G., Young, A.P., and Oberdick, J. (2007) A promoter element with enhancer properties, and the orphan nuclear receptor RORa, are required for Purkinje cell-specific expression of a Gi/o modulator. Mol. Cell. Neurosci. 34, 324-342.

Schonberg DL, Popovich P.G, McTigue D.M. (2007) Oligodendrocyte genesis is differentially influenced by Toll-like receptor (TLR2) and TLR4 mediated intraspinal macrophage activation., J Neuropath Exp Neurol, 66(12): 1124-1135.

Trainor, B.C., Lin, S., Finy, M.S., Rowland, M.R. & Nelson, R.J.  (2007).  Photoperiod reverses the effects of estrogen on male aggression via genomic and non-genomic pathways.  Proceedings of the National Academy of Sciences (USA) 104, 9840-9845.

Tripathi R, McTigue DM. (2007) Prominent oligodendrocyte genesis along the border of spinal contusion lesions. Glia, 55:698-711.

Wechselberger, M., C.L. Wright, G.A. Bishop and J.A. Boulant. (2006).  Ionic channels and conductance-based models of hypothalamic neuronal thermosensitivity. American Journal of Physiology 291: R518-R529.

Weil, Z.M., Bowers, S.L., Pyter, L.M. and Nelson, R.J.  (2006). Social interactions alter proinflammatory cytokine gene expression and behavior following endotoxin administration. Brain Behavior and Immunity, 20:72-79.

Weil, Z.M., Bowers, S.L., Dow, E.R., and Nelson, R.J.  (2006).  Maternal aggression persists following lipopolysaccharide-induced activation of the immune system.  Physiology & Behavior, 87: 694-699.

Weil, Z.M., Martin, L.B., and Nelson, R.J. (2006). Photoperiod differentially affects immune function and reproduction in collared lemmings (Dicrostonyx groenlandicus). Journal of Biological Rhythms, 21:384-393.

Weil, Z.M., Huang, A.S., Beigneux, A., Kim, P.M., Molliver, M.E., Blackshaw, S., Young, S.G., Nelson, R.J. and Snyder, S.H. (2006). Behavioural alterations in male mice lacking the gene for D-aspartate oxidase. Behavioural Brain Research, 171:295-302.

Weil, Z.M., Pyter, L.M., Martin, L.B. and Nelson, R.J. (2006). Perinatal photoperiod organizes adult immune responses in Siberian hamsters (Phodopus sungorus). American Journal of Physiology, 290: R1714-R1719.

Weil Z.M., Su A.J., Barker J.M., Karelina K., Nelson R.J., and DeVries A.C., (submitted). Time-of-Day Determines Neuronal Damage and Mortality after Cardiac Arrest.

Weil, Z.M., Kidder, S.L., and Nelson, R.J.  (2007) Photoperiod alters affective responses in collared lemmings.  Behavioural Brain Research, 179: 305–309.

Wechselberger, M., C.L. Wright, G.A. Bishop and J.A. Boulant. (2006).  Ionic channels and conductance-based models of hypothalamic neuronal thermosensitivity.  American Journal of Physiology 291: R518-R529.

Wright, C.L. and J.A. Boulant. (2007).  Carbon dioxide and pH effects on temperature sensitive and hypothalamic insensitive neurons. Journal of Applied Physiology 102: 1357-1366.

Wright, C.L., P.W. Burgoon, G.A. Bishop and J.A. Boulant.(2008). Cyclic GMP effects on temperature sensitive and insensitive hypothalamic neurons. American Journal of Physiology  [Articles in Press, March 5, 2008].

Xiao, R., Tian J.B., Tang, J. and Zhu, M.X. (2008) The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active. Cell Calcium. 43:334-43.

Xiao, R., Tang, J., Wang, C., Colton, C.K., Tian, J. and Zhu, M.X. (2008) Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations. J Biol Chem. 283:6162-74

Xu, M., Cao, R., Xiao, R., Zhu, M.X., and Gu, C. (2007) The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G. J. of Neurosci. 27:14158-14170.

Papers (published; used the core grant but did not cite it)

Huang, A.S., Beigneux, A., Weil, Z.M., Kim, P.M., Molliver, M.E. Blackshaw, S., Nelson, R.J., Young, S.G. &. Snyder, S.H. (2006).  D-Aspartate regulates melanocortin formation and function: Behavioral alterations in D-aspartate oxidase–deficient mice.  Journal of Neuroscience, 26:2814–2819.

Nishijima, I., Yamagata, T., Spencer, C., Weeber, E., Alekseyenko, O., Sweatt, J. et al. (2006). Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior. Human Molecular Genetics, 15(21), 3241-50.